Pubblicazioni scientifiche

Autori

Titolo

Pubblicazione

A. Arvola, M. Vassallo, M. Dean, P. Lampila, A. Saba, L. Lähteenmäki and R. Shepherd

Predicting intentions to purchase organic food: The role of affective and moral attitudes in the theory of planned behaviour

Abstract

Appetite, In Press, Accepted Manuscript, Available online 1 October 2007

M. Carbonaro

Bioactivity of legume components

Grain Legumes (2007), XX

F. Paoletti, N. Nardo, L. D'Evoli, M. Carbonaro

Effetto della conservazione sulla consistenza e le caratteristiche funzionali e della frazione azotata di Mozzarella di bufala campana

Ricerche e innovazioni nellindustria alimentare, Vol. VIII, Chiriotti Ed., Pinerolo Italia (2007), XX.

M. Carbonaro, L. D'Evoli, A. Aguzzi

Potenziale nutrizionale di nuove linee di fagiolo e varieta locali di leguminose minori

Ricerche e innovazioni nellindustria alimentare, Vol. VIII, Chiriotti Ed., Pinerolo Italia (2007) (in corso di pubblicazione).

M. Carbonaro e A. Nucara

Application of FT-IR spectroscopy in the assessment of changes in the secondary structure of food proteins taking legumes as a model

Amino Acids (2007), 33, 45-46.

M. Carbonaro

Le proprietà nutrizionali del Phaseolus vulgaris L.: caratterizzazione del fagiolo di Lamon IGP

Agroindustria (2007), 6(1), 147-150.

S. De Henauw, F. Gottrand, I. De Bourdeaudhuij, C. Leclercq, A. Kafatos, D. Molnar, A. Marcos, J. Dallongeville, C. C. Gilbert, P. Bergman, C. Breidenassel, M. Kersting & L. A. Moreno

Nutritional status and lifestyles of adolescents from a public health perspective. The HELENA ProjectHealthy Lifestyle in Europe by Nutrition in Adolescence.

Abstract disponibile:

http://www.springerlink.com/content/u1707h13166u0h9w/

J Public Health (2007) 15:187197

M Roselli, A Finamore, M S Britti, S R Konstantinov, H Smidt, W M de Vos and E Mengheri.

The novel porcine Lactobacillus sobrius strain protects intestinal cells from enterotoxigenic Escherichia coli K88 infection and prevents membrane barrier damage.

J. Nutr accepted.

Roselli M., Britti M.S., Le Huërou-Luron I. and Mengheri E.

Effect of different plant extracts and natural substances (PENS) against membrane damage induced by enterotoxigenic E. coli k88 in pig intestinal cells.

Toxicol. In Vitro, 2007, 21:224-229.

D'Evoli,L., Cocchiola, M., Lucarini, M., Aguzzi, A., Gabrielli, P. and Lombardi-Boccia, G.

Nutritional quality of strawberries (Fragaria ananassa, cv.favette) from biodynamic and conventional agriculture.

(2007) Proceeding VI International Symposium Food and Agricultural Products: Processing and Innovations CIGR.

Massimo Lucarini, Laura D'Evoli, Sabina Lanzi and Ginevra Lombardi-Boccia

Antioxidant activity and distribution of ascorbic acid and flavonols in pulp and skin of yellow plums (Prunus domestica, L.) related to agricultural system and light exposure In:

(2007) Proceeding VI International Symposium Food and Agricultural Products: Processing and Innovations CIGR

D'Evoli. L., Lucarini, M., Aguzzi, A., Gabrielli. P., Nicoli, S., Marletta, L. and Lombardi-Boccia G.

Heme-iron as quality marker in meat-based dishes.

3rd International Symposium FESTEM Santiago de Compostela dal 16 al 20 Maggio 2007

Ranaldi, G., Mancini, E., Ferruzza, S., Sambuy, Y., and Perozzi, G.

Effects of red wine on ochratoxin A toxicity in intestinal Caco-2/TC7 cells. Abstract Ochratoxin A (OTA) is found in a variety of foods and beverages, including red wine. OTA was reported to be nephrotoxic, immunotoxic, hepatotoxic and a potential carcinogen, with yet uncharacterized mechanisms. Consumption of contaminated wines might contribute up to 13% of OTA daily human intake. Potentially chronic exposure has therefore raised public health concern. OTA toxicity in the presence of de-alcoholated red wine was investigated in human intestinal Caco-2/TC7 cells, differentiated on filter supports, by measuring tight junction (TJ) permeability, morphological alterations of TJ proteins and occurrence of apoptosis. Cells were treated with OTA, in the presence of de-alcoholated red wine, for 48h and the ability to recover from the effects of OTA was evaluated after 24h in complete medium. OTA treatment increased TJ permeability and caused intracellular redistribution of claudin-4. However, cells were able to restore permeability and correct localization of claudin-4 following 24h recovery. Conversely, in the presence of red wine, OTA produced faster and irreversible increase in TJ permeability, intracellular delocalization of claudin-4 and extensive apoptosis. Our results point at a possible synergy between OTA and some red wine components, such as polyphenols, in the induction of apoptotic cell death.

(2007). Toxicol In Vitro 21, 204-210.

Canali R, Scaccini C, Ambra R, Mattivi F, Scaccini C, Virgili F.

A novel model to study the biological effects of red wine at molecular level.

British Journal of Nutrition 2007.

Natella F., Fidale M., Tubaro F., Ursini F., Scaccini C.

Selenium supplementation prevents the postprandial increase of atherogenic electronegative LDL.

Nutrition Metabolism and Cardiovascular disease 13, 2007

Nardini M., Natella F., Scaccini C., Ghiselli A.

Role of dietary polyphenols in platelet aggregation. A review of the supplementation studies.

Platelets 18(3): 224-243, 2007

Leonardi F., Attorri L., Di Benedetto R., Di Biase A., Sanchez M., Pellizzari Tregno F., Nardini M., Salvati S.

Docosahexaenoic acid supplementation induces dose and time dependent oxidative changes in C6 glioma cells.

Free Radic. Res. 41: 748-756, 2007.

Natella F., Nardini M., Belelli F., Scaccini C.

Coffee drinking induces incorporation of phenolic acids into LDL and increases the resistance of LDL to ex vivo oxidation in humans.

Am. J Clin. Nutrition 2007 86(3):604-9.

Raffo A., Baiamonte I., Paoletti F.

Changes in antioxidants and taste-related compounds content during cold storage of fresh-cut red sweet peppers.

Abstract: Abstract

European Food Research and Technology 2007 (published online 3/5/07).

Raffo A., Nardo N., Tabilio M.R., Paoletti F.

"Effects of Cold Storage on Aroma Compounds of White- and Yellow-Fleshed Peaches"

Abstract: Abstract

European Food Research and Technology (published online 5/7/2007)

Raffo A., Baiamonte I., Nardo N. & Paoletti F.

Internal quality and antioxidants content of cold stored red sweet peppers as affected by polyethylene bag packaging and hot water treatment

Abstract: Abstract

European Food Research and Technology 225, 395-405, 2007.

Carabelli M, Possenti M, Sessa G, Ciolfi A, Sassi M, Morelli G,Ruberti I.

Canopy shade causes a rapid and transient arrest in leaf development through auxin-induced cytokinin oxidase activity. Institute of Molecular Biology and Pathology, National Research Council, 00185 Rome, Italy. A plant grown under canopies perceives the reduction in the ratio of red (R) to far-red (FR) light as a warning of competitio n, and enhances elongation growth in an attempt to overgrow its neighbors. Here, we report that the same low R/FR signal that induces hypocotyl elongation also triggers a rapid arrest of leaf primordium growth, ensuring that plant resources are redir ected into extension growth. The growth arrest induced by low R/FR depends on auxin-induced cytokinin breakdown in incipient vein cells of developing primordia, thus demonstrating the existence of a previously unrecognized regulatory circuit underlyi ng plant response to canopy shade. PMID: 17671088 [PubMed - in process]

Genes Dev. 2007 Aug 1;21(15):1863-8.

Farina L, De Santis A, Morelli G, Ruberti I.

Dynamic measure of gene co-regulation. Dipartimento di Informatica e Sistemistica Antonio Ruberti, Università di Roma La Sapienza, Via Eudossiana 18, Rome 00184, I taly. lorenzo.farina@uniroma1.it Gene expression is to a large extent controlled at the level of mRNA accumulation. Genes whose products function together are likely under a common regulatory system (e.g., signal transduction pathways, sets of regulatory proteins) such that they are expressed in a coordinated manner. This property has been frequently used in the analysis of genome-wide expression data, as the experimental observation that a group of genes is co-expressed frequently implies that the genes share a common regulato ry mechanism. The authors have investigated the situation in which dissimilarity in gene-expression time profiles may still r esult from the presence of the same regulatory signal, as in the case of common transcription factors. To this aim, a dynamic model that takes into account the effect of specific mRNA degradation on the shape of gene-expression time series has been d eveloped, and the concept of 'dynamically co-regulated' genes has accordingly been introduced as the goodness-of-fit to such a model (called dynamic R2). The statistical analysis of dynamic R2 over a number of different experimental data sets and org anisms shows that the presence of dynamically co-regulated genes is by far more significant than that expected from the rando mised data. Furthermore, as an example of the usefulness of the proposed method, genome-wide yeast measurements such as cell- cycle time series and transcription factors targets data, were used to prove that dynamic co-regulation is statistically rela ted to the presence of common transcription factor(s). This latter property is very useful when trying to infer computational indications of co-regulation for not-yet annotated genes that do not display a co-expression pattern. PMID: 17370425 [PubMed - indexed for MEDLINE]

IET Syst Biol. 2007 Jan;1(1):10-7.

M. Dean, R. Shepherd, A. Arvola, M. Vassallo, M. Winkelmann, E. Claupein, L. Lähteenmäki, M.M. Raats and A.Saba

Consumer perceptions of healthy cereal products and production methods.

Abstract

Journal of Cereal Science, In Press, Corrected Proof, Available online 27 June 2007

A. Arvola, L. Lähteenmäki, M. Dean, M. Vassallo, M. Winkelmann, E. Claupein, A. Saba and R. Shepherd

Consumers beliefs about whole and refined grain products in the UK, Italy and Finland. Abstract

Journal of Cereal Science, In Press , Corrected Proof, Available online 16 June 2007

Kristallis A., Vassallo M., Chryssohoidis G. and Perrea T.

To Buy or no to Buy Organic Food? Societal and Individualistic Drivers as Predictors of Organic Purchasing Revealed through a Portrait Value Questionnaire (PVQ)-based Inventory.

(2007). Journal of Consumer Behaviour, (in press).

Macone A., Caiazzo A., Antonucci A., Fochi, I., Nardini M., Duprè S., Matarese R.M.

Synthesis and characterization of a dehydrogenation product arising from the oxidation of aminoethylcysteine ketimine decarboxylated dimer.

J. Natural Products

Hininger-Favier I., Andriollo-Sanchez M., Arnaud J., Meunier N., Bord S., Graham C., Polito A., Maiani G., OConnor J.M., Coudray C. and Russel A.M.

Age and sex dependent effects of long term zinc supplementation on essential trace element status and lipid metabolism in European subjects.

The ZENITH study. B.J.N. 97: 569-578, 2007

Intorre F., Maiani G., Cuzzolaro M., Simpson E.E.A., Catasta G., Ciarapica D., Mauro B., Toti E., Zaccaria M., Coudray C., Corelli S., Palomba L. and Polito A.

Descriptive data on lifestyle, anthropometric status and mental health in Italian elcerly people.

J.N.H.A. 11 (2): 165-174, 2007

Azzini E., Bugianesi R., Romano F., Di Venere D., Miccadei S., Durazzo A., Foddai M.S., Catasta G., Linsalata V. and Maiani G.

Absorption and metabolism of bioactive molecules after oral consumption of cooked edible heads of Cynara scolymus L. (cv 3 Violetto di Provenza) in humans: a pilot study .

B.J.N. 97: 963-969, 2007

Stewart-Knox B.J., Simpson E.E.A., Parr H., Rae G., Polito A., Intorre F., Andriollo-Sanchez M., Meunier N, OConnor J.M., Maiani G., Coudray C. and Strain J.J.

Taste acuity in response to zinc supplementation in older Europeans

Brit. J. Nutr. 26: 1-8, 2007

Miccadei S., Di Venere D., Cardinali A., Romano F., Bugianesi R., Foddai M.S., Fraioli R., Mobarhan S. and Maiani G.

Antioxidative and apoptotic of polyphenols exctracts from edible part of the artichoke (Cynara scolymus L.) on cultured rat hepatocytes and on human hepatoma cells.

Nutrition and Cancer 2007 (in press)

Andriollo-Sanchez M., Hininger-Favier I., Meunier N., Venneria E., OConnor J.M., Phil D., Maiani G., Polito A., Bord Engineer S., Ferry M., Coudray C. and Roussel A.M.

No antioxidant beneficial effect of zinc supplementation on oxidative stress markers and antioxidant defenses in middle-aged and elderly subjects. The ZENITH study.

American College Nutrition 2007 (in press)

Maiani G., Periago Castón M.J., Catasta G., Toti E., Goñi Cambrodón I., Bysted A., Granado-Lorencio F., Olmedilla-Alonso B., Knuthsen P., Valoti M., Böhm V., Mayer-Miebach E., Behsnilian D. and Schlemmer U.

Carotenoids: actual knowledge and their protective role in humans (Review). (submitted)

2007

Cermak R., Durazzo A., Maiani G., Böhm V., Kammerer D.R., Carle R., Wiczkowski W., Piskula M.K. and Galensa R.

The influence of post-harvest processing and storage of foodstuffs on the bioavailability of flavonoids and phenolic acids. (Review). (submitted)

2007

Intorre F., Polito A., Andriollo-Sanchez M., Azzini E., Raguzzini A., Toti E., Zaccaria M., Catasta G., Meunier N., Ducros V., O'Connor J.M., Coudray C., Roussel A.M. and Maiani G.

Effect of zinc supplementation on vitamin status of middle-aged and older European adults. The ZENITH project.

European Journal of Clinical Nutrition 2007 (in press).

Breidenassel C, Al-Tahan J, Spinneker A, Segoviano M, Gómez S, Ferrari M, Beghin L, Pietrzik K, Stehle P, González-Gross M.

Assessments of nutritional biomarkers in fresh blood samples in an international multi-center study: a challenge for a handling and transport system.

Abstract disponibile:

Abstract

FENS 2007, Paris.

Leclercq C.

Issues arising when methods used to asses dietary exposure to flavouring substances are compared.

Food and Chemical Toxicology (2007) 45, 2336-2337.

Cialfa E., Sette S., Mariani Costantini A.

Dati relativi ad alcune principali statistiche vitali e alle modifiche dei profili alimentari nei venticinque Paesi dellUnione Europea.

Abstract

Alimentazione e Nutrizione Umana eds. A. Mariani Costantini, C. Cannella, G. Tomassi, Roma: Il Pensiero Scientifico Seconda Edizione, 2006, pp. 673-700.

M.Carbonaro

Application of two-dimensional electrophoresis for monitoring gastrointestinal digestion of milk.

Amino Acids (2006), 31, 485-488.

M. Carbonaro, M. Mattera, G. Di Lullo, P. Gabrielli

Proprietà della componente proteica e minerale di cereali e prodotti lattiero-caseari nazionali tipici.

Ricerche e innovazioni nellindustria alimentare, Vol. VII, Chiriotti Ed., Pinerolo Italia (2006), pp. 410-414.

M. Carbonaro

Markers of buffalo mozzarella cheese detected by capillary electrophoresis.

It. J. Biochem. (2006), 55, 407.

M. Carbonaro

7S globulins from Phaseolus vulgaris L.: impact of structural aspects on the nutritional quality. Biosci. Biotech.

Biochem. (2006), 70, 2620-2626.

Roselli M., Britti M.S., Finamore A. and Mengheri E.

Role of probiotics and prebiotics on immunity, allergy and inflammatory disease.

Nutrition and Immunity Eds. Elena Mengheri, Marianna Roselli, Maria Serena Britti and Alberto Finamore, 2006, pp. 53-70.

Britti MS Roselli M., Finamore A., Merendino N. And Mengheri E.

Regulation of intestinal and peripheral immune response by probiotics

J. Biologia, 2006, 61:1-6.

Marianna Roselli, Alberto Finamore, Maria Serena Britti and Elena Mengheri.

The probiotic bacteria Bifidobacterium animalis MB5 and Lactobacillus rhamnosus GG protect Caco-2 cells from inflammation induced by enterotoxigenic Escherichia coli K88.

Brit. J. Nutr. 2006, 95: 1-9.

Rachele Ciccocioppo, Alberto Finamore, Carmen Ara, Antonio Di Sabatino Elena Mengheri, Gino R. Corazza.

Altered expression, localization and phosphorylation of epithelial junctional proteins in celiac disease.

Am. J. Clin. Pathol. 2006, 125: 502-405.

Menotti A., Lanti M., Maiani G. and Kromhout D.

Determinatns of longevity and all-causes mortality among middle men. The role of 48 personal characteristics in a 40 year follow-up of the Italian rural areas of the seven countries study.

Aging Clinical Exp. Res 18 (5): 394-406, 2006

Lucarini M., Lanzi, S., Aguzzi A. and Lombardi-Boccia G.

(2006) Daily Intakes of Vitamin A and Carotenoids in Italy.

Int. J. Vit. and Nutr. Res.76,3 :103-109

D'Evoli ., Huikko, L., Lampi, A.-M., Lucarini, M., Lombardi-Boccia G., and Piironen V.

(2006) Influence of rosemary (Rosmarinus officinalis, L.) on plant sterol oxidation in extra-virgin olive oil.

Molecular Nutrition & Food Research 50:818-823

D'Evoli, L., Salvatore, P., Nicoli, S., Gabrielli, L., Marletta. L. e Lombardi-Boccia, G.

(2006). Influenza della cottura e degli ingredienti sulla composizione della frazione lipidica e vitaminica di ricette tradizionali a base di carne.

Atti del VI Congresso Nazionale di Chimica degli Alimenti

Carnevale E., Sambuy Y.

(2006) Dagli alimenti ai nutrienti. In Alimentazione e Nutrizione Umana A. Mariani-Costantini, C. Cannella, G. Tomassi, ed. Seconda Edizione. Abstract

Il Pensiero Scientifico Editore. pag. 167-214.

Scarino, ML

(2006) A Sideways Glance: Ubiquitous yet still elusive? Abstract

Genes & Nutrition 1(2), -74.

Sambuy Y.

(2006) A Sideways Glance: Perilipin a central and multifaceted protein in adipose lipid metabolism. Abstract

Genes & Nutrition 1(3/4), 141-142

Virgili F, Perozzi G.

Editorial: An -omic perspective.

Genes and Nutrition;1:3-5, 2006.

Saarinen NM, Mäkelä S, Penttinen P, et al.

Tools to evaluate estrogenic potency of dietary phytoestrogens: a consensus paper from the EU Thematic network "Phytohealth" (QLKI-2002-2453).

Genes and Nutrition;1, 2006.

Virgili F, Perozzi G.

From phytoestrogens to obesity and the metabolic syndrome: health from food and food for health.

Genes and Nutrition;1, 2006.

Ambra R, Rimbach G, De Pascual-Teresa S, et al.

Genistein affects the expression of genes involved in blood pressure regulation and angiogenesis in primary human endothelial cells.

Nutr Metab Cardiov Dis;16:35-43, 2006.

Cimino F, Ambra R, Canali R, Saija A, Virgili F.

Effect of Cyanidin-3-O-Glucoside on UVB Induced response in Human Keratinocytes.

J Agric Food Chem;54:4041-4047, 2006.

Nardini M., Natella F., Scaccini C., Ghiselli A.

Phenolic acids from beer are absorbed and extensively metabolized in humans.

J. Nutr. Biochem;17(1):14-22, 2006

Pignatelli P., Ghiselli A., Buchetti B., Carnevale R., F. Natella , Germanò G., Fimognari F., S. Di Santo , Violi F.

Polyphenols synergistically inhibit oxidative stress in subject given red and white wine.

Atherosclerosis Sep;188(1):77-83, 2006

Natella F., Nardini M., Virgili F., Scaccini C.

Role of dietary polyphenols in the platelet aggregation network- a review of the in vitro studies.

Nutraceutical Research 4(1): 1-22, 2006

Raffo A., Sinesio F., Moneta E., Nardo N., Peparaio M. & Paoletti F.

Internal quality of fresh and cold stored celery petioles described by sensory profile, chemical and instrumental measurements

Abstract: Abstract

European Food Research and Technology 222, 590-599, 2006.

Raffo A., La Malfa G., Fogliano V., Maiani G and Quaglia G.

Seasonal variations in antioxidant components of cherry tomatoes (Lycopersicon esculentum Cv. Naomi F1)

Full text

Journal of Food Composition and Analysis, 19, 11-19, 2006.

Ruberti I, Sessa G, Morelli G.

Functional analysis of transcription factors by microparticle bombardment. Dept. of Genetics and Molecular Biology, Istituto di Biologia e Patologia Molecolari CNR, University of Rome La Sapienza, Ita ly. This chapter describes a method for rapid gene expression assays in Arabidopsis. Three distinct plasmids are codelivered into leaves by microparticle bombarment. The first one carries a transacting factor gene driven by the cauliflower mosaic virus ( CaMV) 35S promoter. The second plasmid includes a reporter luciferase (LUC) gene transcribed from a promoter containing the T F binding site(s). The third plasmid contains a reference beta-glucuronidase (GUS) gene transcribed from the 35S-CaMV promote r, which is used to normalize data derived from independent experiments. This method could be applied to study systematically the functional properties of Arabidopsis transcription factors as well as to identify promoters and control region(s) regula ted by specific transcription factors. PMID: 16739581 [PubMed - indexed for MEDLINE]

Methods Mol Biol. 2006;323:231-6.

Ambra R., Salvi S., Marcelli M. e Morelli G.

Organismi Geneticamente Modificati: tecniche di produzione e di rilevame nto.

(2006). Sapere 5, 22-28

Ambra R., Marcelli M. e Morelli G.

Tracciabilità degli OGM negli alimenti.

(2006). Agrobiotecnologie nel contest o italiano INRAN. 441-448

M. Dean, A. Arvola, M. Vassallo, L. Lähteenmäki, M.M. Raats, A. Saba and R. Shepherd

Comparison of elicitation methods for moral and affective beliefs in the theory of planned behaviour.

Abstract

Appetite, Volume 47, Issue 2, September 2006, Pages 244-252

Raffo A., La Malfa G., Fogliano V., Maiani G. and Quaglia G.

Seasonal variations of quality attributes and antioxidant content in cherry tomatoes (Lycopersicon Cv Naomi F1).

J. of Food Composition and Analysis 19: 11-19, 2006

Feillet-Coudray C., Meunier N., Bayle D., Andriollo-Sanchez M., O'Connor J.M., Maiani G., Roussel A.M., Mazur A. and Coudray C.

Effect of zinc supplementation on in vitro Cu-induced oxidation of low density lipoproteins in French subjects. The ZENITH study.

B.J.N. 95 :1134-1142, 2006

Fanasca S., Colla G., Maiani G., Venneria E., Rouphael Y., Azzini E. and Saccardo F.

Changes in antioxidant content of tomato fruits in response to cultivar and nutrient solution composition.

J. Agric. Food Chemistry 54 (12): 4319-4325, 2006

Fanasca S., Colla G., Rouphael Y., Saccardo F., Maiani G., Venneria E. and Azzini E.

Evaluation of nutritional value of two tomato genotypes grown in soilless culture as affected by macrocation proportions.

Hort. Science 41 (7): 1584- 1588, 2006

Rossi L., Maiani G. and Pastore G.

Le agrobiotecnologie nel contesto italiano. Aspetti Nutrizionali.

Agro biotecnologie: 263-278, 2006

Sutera M., Perna F., Bonifazi F., Simpson E.E.A., Maiani G., Intorre F., Polito A. and Cuzzolaro M.

Cognitive impairment and depressive symptoms in the population of 348 elderly.

Giornale di Gerontologia 54 (4): 223-226, 2006

van Apeldoorn ME, Pronk MEJ, Leclercq C, Le Donne C, Olempska-Beer Z. and Hattan D.

Hexose oxidase from chondrus crispus expressed in Hansenula polymorpha. Safety evaluation of certain food additives.

Volume disponibile:

Abstract

WHO Food Additives Series: 54. Sixty third meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), WHO, Geneva, 2006, p. 37-47.

van Apeldoorn ME, Pronk MEJ, Leclercq C, Olempska-Beer Z. and Hattan D.

Xylanases from Bacillus subtilis expressed in B. subtilis. Safety evaluation of certain food additives.

Volume disponibile:

Abstract

WHO Food Additives Series: 54. Sixty third meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), WHO, Geneva, 2006, pp. 149-157.

Williams G, Leclercq C and Knaap AGAC.

Glycyrrhizinic acid. Safety evaluation of certain food additives.

Volume disponibile:

Abstract

WHO Food Additives Series: 54. Sixty third meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), WHO, Geneva, 2006, pp. 561-620.

A Finamore, C Devirgiliis, D Panno, M. D'Aquino, A Polito, E Venneria, A. Raguzzini, C Coudray and E Mengheri.

Immune response in relation to zinc status, sex and antioxidant defence in Italian elderly population: The ZENITH study.

Eur. J. Clin: Nutr. 2005, 59: S68-S72.

Roselli Marianna, Finamore Alberto, Britti Maria Serena, Bosi Paolo, Oswald Isabelle and Mengheri Elena

Alternatives to in-feed antibiotics: evaluation of probiotics, zinc or organic acids as protective agents for the intestinal mucosa. Comparison of in vitro with in vivo results.

Anim. Res. 2005, 54: 1-16.

Lombardi-Boccia , G., Lanzi, S. Aguzzi, A.

Aspects of Meat Quality: Trace Elements and B Vitamins in Raw and Cooked Meats

(2005) J. Food Comp. Anal.18:39-46.

Arcella D. and Leclercq C.

Assessment of dietary intake of flavouring substances within the procedure for their safety evaluation: advantages and limitations of estimates obtained by means of a per capita method.

Abstract disponibile: Abstract

Food and Chemical Toxicology; 43, 105-116, 2005.

Lucarini, M. D'Evoli, L., Salvatore, P., Aguzzi, A., Nicoli, S., Gabrielli, L., Marletta. L. e Lombardi-Boccia, G.

Influenza del grado di maturazione e delle condizioni pedoclimatiche sul profilo e sulla concentrazione delle antocianine in una cultivar di ciliegie (Prunus avium l.) siciliana.

(2005). Ricerche e Innovazioni nellIndustria Alimentare Vol.VII (Chiriotti ed.)

Arcella D., Le Donne C. and Leclercq C.

Dietary exposure to chemicals within the process of risk assessment: possible applications to substances that may cause allergic reactions.

Abstract disponibile:

Abstract

(2005) Proceedings of the Nutrition Society, 64, 418-25.

Leclercq C., Le Donne C., Arcella D., D'Addezio L., Turrini A.

Esposizione a sostanze chimiche presenti della dieta in età pediatrica.

Volume disponibile:

Abstract

2005 Sicurezza alimentare e salute dellinfanzia. Rapporti ISTISAN 35, 24-38.

D'Evoli ., Huikko, L., Lampi, A.-M., Lucarini, M., Lombardi-Boccia G., and Piironen V.

Influence of an olive oil rosemary extract on plant sterol oxidation.

(2005) Cost Action 927 Thermally processed Foods: possibile Health implications. Hamburg, Septemberr 23-24

Predieri, G., Elviri, L., Tegoni, M., Zagnoni, I., Cinti, E., Biagi, G., Ferruzza, S., and Leonardi, G.

Metal chelates of 2-hydroxy-4-methylthiobutanoic acid in animal feeding. Part 2: Further characterizations, in vitro and in vivo investigations.

AbstractThe alpha-hydroxyacid 2-hydroxy-4-methylthiobutanoic acid (the so-called methionine hydroxy-analogue, MHA), largely used in animal nutrition as a source of methionine, forms stable metal chelates with divalent metals of formula [{CH(3)SCH(2) CH(2)CH(OH)COO}(2)M].nH(2)O. Protonation and iron(III) and copper(II) complex formation constants have been determined by potentiometry at 25 degrees C. Distribution diagrams show that no free Fe(3+) cations are present in solution at pH>2.5. ESI-MS (Electron-Spray Ionization Mass Spectrometry) investigations carried out both on iron and zinc complexes in solution have evidenced various species with different MHA/metal ratios. In vivo trials were carried out with rats. After receiving a zinc-deficient diet for 3 weeks, animals were fed the same diet added with zinc sulfate or zinc/MHA chelate; the zinc content of faeces was higher (+45%; P<0.05) in sulfate fed rats, whereas zinc retention was higher (+61%; P<0.05) in the Zn/MHA diet. Experiments in vitro with human intestinal Caco-2 cells indicated that the MHA/Fe chelate was taken up by the cells without any apparent toxic effect. The iron uptake was higher than that of iron nitrilotriacetate (Fe(3+)NTA), an effective chelate for delivering iron to milk diets. In conclusion, these data indicate that the use of MHA chelates could be a valuable tool to increase bioavailability of trace minerals and reduce the environmental impact of animal manure.

(2005). J Inorg Biochem 99, 627-636

Sambuy, Y., De Angelis, I., Ranaldi, G., Scarino, M. L., Stammati, A., and Zucco, F.

The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics.

Abstract The human intestinal Caco-2 cell line has been extensively used over the last twenty years as a model of the intestinal barrier. The parental cell line, originally obtained from a human colon adenocarcinoma, undergoes in culture a process of spontaneous differentiation that leads to the formation of a monolayer of cells, expressing several morphological and functional characteristics of the mature enterocyte. Culture-related conditions were shown to influence the expression of these characteristics, in part due to the intrinsic heterogeneity of the parental cell line, leading to selection of sub-populations of cells becoming prominent in the culture. In addition, several clonal cell lines have been isolated from the parental line, exhibiting in general a more homogeneous expression of differentiation traits, while not always expressing all characteristics of the parental line. Culture-related conditions, as well as the different Caco-2 cell lines utilized in different laboratories, often make it extremely difficult to compare results in the literature. This review is aimed at summarizing recent, or previously unreviewed, data from the literature on the effects of culture-related factors and the influence of line sub-types (parental vs. different clonal lines) on the expression of differentiation traits important for the use of Caco-2 cells as a model of the absorptive and defensive properties of the intestinal mucosa. Since the use of Caco-2 cells has grown exponentially in recent years, it is particularly important to highlight these methodological aspects in order to promote the standardization and optimisation of this intestinal model.

(2005). Cell Biol Toxicol 21, 1-26

Zucco, F., Batto, A. F., Bises, G., Chambaz, J., Chiusolo, A., Consalvo, R., Cross, H., Dal Negro, G., de Angelis, I., Fabre, G., Guillou, F., Hoffman, S., Laplanche, L., Morel, E., Pincon-Raymond, M., Prieto, P., Turco, L., Ranaldi, G., Rousset, M., Sambuy, Y., Scarino, M. L., Torreilles, F., and Stammati, A.

An inter-laboratory study to evaluate the effects of medium composition on the differentiation and barrier function of Caco-2 cell lines.

Abstract Differentiated human intestinal Caco-2 cells are frequently used in toxicology and pharmacology as in vitro models for studies on intestinal barrier functions. Since several discrepancies exist among the different lines and clones of Caco-2 cells, comparison of the results obtained and optimisation of models for use for regulatory purposes are particularly difficult, especially with respect to culture conditions and morphological and biochemical parameters. An inter-laboratory study has been performed on the parental cell line and on three clonal Caco-2 cell lines, with the aim of standardising the culture conditions and identifying the best cell line with respect to parameters relevant to barrier integrity, namely, trans-epithelial electrical resistance (TEER) and mannitol passage, and of epithelial differentiation (alkaline phosphatase activity). Comparison of the cell lines maintained in traditional serum-supplemented culture medium or in defined medium, containing insulin, transferrin, selenium and lipids, showed that parameter performance was better and more reproducible with the traditional medium. The maintenance of the cell lines for 15 days in culture was found to be sufficient for the development of barrier properties, but not for full epithelial differentiation. Caco-2/TC7 cells performed better than the other three cell lines, both in terms of reproducibility and performance, exhibiting low TEER and mannitol passage, and high alkaline phosphatase activity.

(2005). Altern Lab Anim 33, 603-618.

Totta P, Acconcia F, Virgili F, et al.

Bio-transformation decreases but do not abrogates estrogenic and antitumoral effects of the soy isoflavone daidzein.

J Nutrition;135:2687-93, 2005.

Valacchi G., Pagnin E., Phung A., Nardini M., Schock B.C., Cross C.E. and van der Vliet A.

Inhibition of NFkB activation and IL-8 expression in human bronchial epithelial cells by acrolein.

Antiox. Red. Signal. 7: 25-31, 2005

Leonardi F., Attorri L., Di Benedetto R., Di Biase A., Sanchez M., Nardini M., Salvati S.

Eicosapentaenoic and docosahexaenoic acids affect the oxidative status of C6 rat glioma cells.

Free Rad. Res. 39: 865-874, 2005

Han, D., Canali, R., Garcia, J., Aguilera, R., Gallaher, T.K., Cadenas, E.

Sites and mechanisms of aconitase inactivation by peroxynitrite: Modulation by citrate and glutathione

Biochemistry 44 (36), pp. 11986-11996, 2005

Raffo A., Gianferri R., Barbieri R. and Brosio E.

Ripening of banana fruit monitored by water relaxation and diffusion 1H-NMR measurements

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Food Chemistry 89 (1), 149-158, 2005.

Sessa G, Carabelli M, Sassi M, Ciolfi A, Possenti M,Mittempergher F, Becker J, Morelli G, Ruberti I.

A dynamic balance between gene activation and repression regulates the shade avoidance response in Arabidopsis. Institute of Molecular Biology and Pathology, National Research Council, 00185 Rome, Italy. Plants grown under dense canopies perceive through the phytochrome system a reduction in the ratio of red to far-red light as a warning of competition, and this triggers a series of morphological changes to avoid shade. Several phytochrome signaling intermediates acting as positive regulators of accelerated elongation growth and induction of flowering in shade avoidance ha ve been identified. Here we report that a negative regulatory mechanism ensures that in the presence of far-red-rich light an exaggerated plant response does not occur. Strikingly, this unpredicted negative regulatory mechanism is centrally involved in the attenuation of virtually all plant responses to canopy shade. PMID: 16322556 [PubMed - indexed for MEDLINE]

Genes Dev. 2005 Dec 1;19(23):2811-5.

Baima, S., Morelli, G.

OGM: Cosa bolle in pentola? Abstract

(2005) Silvae 1 , 86-96.

Morelli, G.

L'identificazione e la quantificazione di OGM e di prodotti derivati.

(2005) Le Biotecnologie e la Qualità della Vita , G. Cantelli Forti e P. Hrelia eds. Collana Alimentazione e Ambiente. Patron Editore Bologna. pp. 309-318

Menotti A., Lanti M., Maiani G. and Kromhout D.

Forty-Year mortality from cardiovascular diseases in the Italian rural areas of the seven countries study.

Acta Cardiol. 60 (5): 521-531, 2005

Meunier N., O'Connor J.M., Maiani G., Cashman K.D., Secker D.L., Ferry M. and Roussel A.M.

Importance of zinc in the elderly. The Zenith study.

Eur. J. Clin. Nutr. 59 suppl 2: S1-S4, 2005

Coudray C., O'Connor J.M., Maiani G., Cashman K.D., Simpson E.E.A., Secker D.L., Ferry M. and Roussel A.M.

Introduction to the Zenith study and summary of baseline results.

Eur. J. Clin. Nutr. 59 suppl 2: S5-S7, 2005

Polito A., Meunier N., Andriollo-Sanchez M., Catasta G., Simpson E.E.A., O'Connor J.M., Roussel A.M., Ferry M., Coudray C. and Maiani G.

Screening and recruitment procedure of late-middle aged and older European subjects. The Zenith study.

Eur. J. Clin. Nutr. 59 suppl 2: S8-S12, 2005

Polito A., Intorre F., Andriollo-Sanchez M., Azzini E., Raguzzini A., Meunier N., Ducros V., O'Connor J.M., Coudray C., RousselA.M. and Maiani G.

Estimation of intake and status of vitamin A, vitamin E and folate in older European adults. The ZENITH study.

Eur. J. Clin. Nutr. 59 suppl 2: S42-S47, 2005

M. Carbonaro, M. Mattera, A. Aguzzi, G. Di Lullo, M. Cappelloni

Potenziale nutrizionale di nuovi prodotti lattiero-caseari ipoallergenici: acquisizioni dal Progetto MiPAF TOLLELAT 2002-2004.

Riv. Sci. Alim. (J. Food Sci. Nutr.)(2005), 1, 29-38.

M. Carbonaro, G. Grant

The absorption of quercetin and rutin in rat small intestine.

Ann. Nutr. Met. (2005), 49, 178-182.

M. Carbonaro, G. Grant, M. Cappelloni

Heat-induced denaturation impairs digestibility of legume (Phaseolus vulgaris L. and Vicia faba L.) 7S and 11S globulins in the small intestine of rat.

J. Sci. Food Agric. (2005), 85, 65-72.

Andriollo-Sanchez M., Hininger-Favier I., Meunier N., Venneria E., O'Connor J.M., Maiani G., C Coudray and Roussel A.M.

Age-related oxidative stress and antioxidant parameters in middle-aged and older European subjects. The Zenith study.

Eur. J. Clin. Nutr. 59 suppl 2: S58-S62, 2005